The Janus Face of VEGF in Stroke.

作者: Samuel Geiseler , Cecilie Morland

DOI: 10.3390/IJMS19051362

关键词: StrokeCerebral arteriesMedicineNeurogenesisIschemiaNeuroinflammationNeuroprotectionPenumbraAngiogenesisBioinformatics

摘要: … Although VEGF-A … VEGF-A to VEGFR-2, as they are the most important in stroke. VEGFR-1 may act as a decoy receptor [17,18], the main effect of which is to prevent the binding of VEGF-…

参考文章(186)
Ann M Stowe, Erik J Plautz, Ines Eisner-Janowicz, Shawn B Frost, Scott Barbay, Elena V Zoubina, Numa Dancause, Michael D Taylor, Randolph J Nudo, VEGF protein associates to neurons in remote regions following cortical infarct Journal of Cerebral Blood Flow and Metabolism. ,vol. 27, pp. 76- 85 ,(2007) , 10.1038/SJ.JCBFM.9600320
Brian P Eliceiri, Robert Paul, Pamela L Schwartzberg, John D Hood, Jie Leng, David A Cheresh, Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability. Molecular Cell. ,vol. 4, pp. 915- 924 ,(1999) , 10.1016/S1097-2765(00)80221-X
Myriam Bernaudin, Anne-Sophie Nedelec, Didier Divoux, Eric T. MacKenzie, Edwige Petit, Pascale Schumann-Bard, Normobaric hypoxia induces tolerance to focal permanent cerebral ischemia in association with an increased expression of hypoxia-inducible factor-1 and its target genes, erythropoietin and VEGF, in the adult mouse brain. Journal of Cerebral Blood Flow and Metabolism. ,vol. 22, pp. 393- 403 ,(2002) , 10.1097/00004647-200204000-00003
Napoleone Ferrara, Hans-Peter Gerber, Jennifer LeCouter, None, The biology of VEGF and its receptors. Nature Medicine. ,vol. 9, pp. 669- 676 ,(2003) , 10.1038/NM0603-669
Jieli Chen, Chunling Zhang, Hao Jiang, Yi Li, Lijie Zhang, Adam Robin, Mark Katakowski, Mei Lu, Michael Chopp, Atorvastatin Induction of VEGF and BDNF Promotes Brain Plasticity after Stroke in Mice Journal of Cerebral Blood Flow & Metabolism. ,vol. 25, pp. 281- 290 ,(2005) , 10.1038/SJ.JCBFM.9600034
Manuel Morales-Ruiz, David Fulton, Grzegorz Sowa, Lucia R. Languino, Yasushi Fujio, Kenneth Walsh, William C. Sessa, Vascular Endothelial Growth Factor–Stimulated Actin Reorganization and Migration of Endothelial Cells Is Regulated via the Serine/Threonine Kinase Akt Circulation Research. ,vol. 86, pp. 892- 896 ,(2000) , 10.1161/01.RES.86.8.892
Hugo J.H. Marti, Myriam Bernaudin, Anita Bellail, Heike Schoch, Monika Euler, Edwige Petit, Werner Risau, HYPOXIA-INDUCED VASCULAR ENDOTHELIAL GROWTH FACTOR EXPRESSION PRECEDES NEOVASCULARIZATION AFTER CEREBRAL ISCHEMIA American Journal of Pathology. ,vol. 156, pp. 965- 976 ,(2000) , 10.1016/S0002-9440(10)64964-4
Catherine N. Hall, Clare Reynell, Bodil Gesslein, Nicola B. Hamilton, Anusha Mishra, Brad A. Sutherland, Fergus M. O’Farrell, Alastair M. Buchan, Martin Lauritzen, David Attwell, Capillary pericytes regulate cerebral blood flow in health and disease Nature. ,vol. 508, pp. 55- 60 ,(2014) , 10.1038/NATURE13165
Alfia A. Khaibullina, Jeffrey M. Rosenstein, Janette M. Krum, Vascular endothelial growth factor promotes neurite maturation in primary CNS neuronal cultures Developmental Brain Research. ,vol. 148, pp. 59- 68 ,(2004) , 10.1016/J.DEVBRAINRES.2003.09.022
Burkhard Hornig, Volker Maier, Helmut Drexler, Physical Training Improves Endothelial Function in Patients With Chronic Heart Failure Circulation. ,vol. 93, pp. 210- 214 ,(1996) , 10.1161/01.CIR.93.2.210