PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis
作者： Katherine Martin , James Pritchett , Jessica Llewellyn , Aoibheann F. Mullan , Varinder S. Athwal
DOI: 10.1038/NCOMMS12502
关键词: Signal transduction 、 Kinase 、 Hepatic stellate cell 、 Protein kinase A 、 Extracellular matrix 、 Cell biology 、 Immunology 、 Myofibroblast 、 Integrin 、 Fibrosis 、 Biology
摘要: … in liver fibrosis in vivo as described by others 18 . Consequently, in this study we have provided in vitro evidence for ITGA11-… remarkably similar to recent data on fibrosis resolution 4,5 . …
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