Analysis of electrical and mechanical left atrial properties in patients with persistent atrial fibrillation

摘要: The study of left atrial (LA) mechanical function during fibrillation (AFib) can provide valuable information, particularly if such profiling is related to the cavity electrical substrate and conveys prognostic information. To assess there any relation between LA asynchrony evaluation be interest in stratifying AFib patients. 50 patients with persistent who underwent cardioversion (CV) were evaluated pre-CV electrograms (AEGs). Electrical was classified according Wells’ patterns AEGs, ranging from most organized (I) dispersed (III) one. addressed by transthoracic 2D-speckle-tracking echo quantified time-to-peak standard deviation (TP-SD) wall strains their peak values (PS) before CV, after 24 h, at 1 month. Pre-CV a linear, inverse TP-SD PS (p < 0.001) direct linear classes = 0.04) observed. With sinus rhythm decreased 0.023) increased 0.001), suggesting improved milieu. A multivariate analysis, testing effects baseline variables predicting post-CV recurrence AFib, revealed that amount variation pre/24 h only independent predictor 6 months 0.046). Speckle tracking-derived parameters describe forces categorizing asynchronous mechanistic profile correlates degree activity. changes pre/post-CV seems have relevance SR maintenance.