Spatially Tuned Neurons in Corvid Nidopallium Caudolaterale Signal Target Position During Visual Search

摘要: The avian pallial endbrain area nidopallium caudolaterale (NCL) shows important similarities to mammalian prefrontal cortex in connectivity, dopamine neurochemistry, and function. Neuronal processing NCL has been studied with respect sensory, cognitive, reward information, but little is known about its role more direct control of motor behavior. We investigated activity during the choice period a delayed match-to-sample task, as 2 trained crows searched selected previously remembered visual target among an array 4 pictures. exhibited behavioral response patterns consistent serial search. Many single neurons were spatially tuned specific positions search directed Moreover, dynamically changed their tuning properties represent different behaviorally relevant task variables across trial. In consecutive periods, responded stimuli, stored stimulus information working memory, guided goal-directed behavior depending on picture, encoded trial outcomes. This flexible encoding all task-relevant aspects executive represents striking convergence neuronal primate cortex. These data highlight key associative areas underlying cognitive corvids primates.