The effects of several vasopressin receptor antagonists on normal intraocular pressure and the intraocular distribution of vasopressin receptor subtypes.
作者： Akira Naito , Takashi Kurasawa , Yasuhiro Ohtake , Yoshihiro Toyoda , Yohji Ezure
DOI: 10.1248/BPB.25.251
关键词: Endocrinology 、 Vasopressin receptor 、 Arginine vasopressin receptor 1A 、 Arginine vasopressin receptor 1B 、 Vasopressin 、 Miosis 、 Neuropeptide 、 Intraocular pressure 、 Vasopressin Antagonists 、 Internal medicine 、 Medicine
摘要: The aim of the present paper is to study relation between vasopressin antagonism and regulation intraocular pressure (IOP). From studies on effect several receptor antagonists, VP-343, OPC-21268, YM087, OPC-31260 SR121463, normal IOP VP-343 pupil diameter in rabbit, it was shown that some antagonists decreased had no influence diameter. A mapping cynomolgus monkey eye revealed a high density binding site for [H3]vasopressin V1 antagonist region iris. These findings suggest should decrease without miosis receptors are
sci-hub.se 参考文章(12)
T Krupin, B Becker, J Levine, A T Barbosa, G W Webb, B Gulli, Central effects of thyrotropin-releasing hormone and arginine vasopressin on intraocular pressure in rabbits. Investigative Ophthalmology & Visual Science. ,vol. 25, pp. 932- 937 ,(1984)
M. Thibonnier, C. Auzan, Z. Madhun, P. Wilkins, L. Berti-Mattera, E. Clauser, Molecular cloning, sequencing, and functional expression of a cDNA encoding the human V1a vasopressin receptor. Journal of Biological Chemistry. ,vol. 269, pp. 3304- 3310 ,(1994) , 10.1016/S0021-9258(17)41863-1
Ferenc László, David De Wied, Ferenc A. László, Pharmacology and clinical perspectives of vasopressin antagonists. Pharmacological Reviews. ,vol. 43, pp. 73- 108 ,(1991)
FREDERIC LACHERETZ, ALAIN BARBIER, CLAUDINE SERRADEIL-LE GAL, PIERRE-PAUL ELENA, JEAN-PIERRE MAFFRAND, GERARD LE FUR, Effect of SR121463, a selective non-peptide vasopressin V2 receptor antagonist, in a rabbit model of ocular hypertension. Journal of Ocular Pharmacology and Therapeutics. ,vol. 16, pp. 203- 216 ,(2000) , 10.1089/JOP.2000.16.203
Alain Morel, Anne-Marie O'Carroll, Michael J. Brownstein, Stephen J. Lolaft, Molecular cloning and expression of a rat V1a arginine vasopressin receptor. Nature. ,vol. 356, pp. 523- 526 ,(1992) , 10.1038/356523A0
Akira NAITO, Yasuhiro OHTAKE, Hisashi HASEGAWA, Yasuhiro FUKAYA, Takashi KURASAWA, Kenji NAITO, Hidehiko MATSUKAWA, Touru OGUMA, Yohji EZURE, Yoshihiro TSURIYA, Hikaru TANAKA, Katsuo KOIKE, Koki SHIGENOBU, Pharmacological Profile of VP-343, a Novel Selective Vasopressin V2 Receptor Antagonist, in Rats. Biological & Pharmaceutical Bulletin. ,vol. 23, pp. 182- 189 ,(2000) , 10.1248/BPB.23.182
M Thibonnier, J M Roberts, Characterization of human platelet vasopressin receptors. Journal of Clinical Investigation. ,vol. 76, pp. 1857- 1864 ,(1985) , 10.1172/JCI112179
D.E Palm, S.G Shue, L.C Keil, C.D Balaban, W.B Severs, Effects of angiotensin, vasopressin and atrial natriuretic peptide on intraocular pressure in anesthetized rats Neuropeptides. ,vol. 29, pp. 193- 203 ,(1995) , 10.1016/0143-4179(95)90061-6
Everton L. Gondim, John H.K. Liu, Vital P. Costa, Robert N. Weinreb, Exogenous vasopressin influences intraocular pressure via the V(1) receptors. Current Eye Research. ,vol. 22, pp. 295- 303 ,(2001) , 10.1076/CEYR.22.4.295.5508
Y Yamamura, H Ogawa, T Chihara, K Kondo, T Onogawa, S Nakamura, T Mori, M Tominaga, Y Yabuuchi, OPC-21268, an orally effective, nonpeptide vasopressin V1 receptor antagonist Science. ,vol. 252, pp. 572- 574 ,(1991) , 10.1126/SCIENCE.1850553