A protein phosphorylation/dephosphorylation network regulates a plant potassium channel

摘要: Potassium (K+) is an essential nutrient for plant growth and development. Plants often adapt to low K+ conditions by increasing their uptake capability. Recent studies have led the identification of a calcium signaling pathway that enables plants act in this capacity. Calcium linked two calcineurin B-like sensors (CBLs) target kinase (CBL-interacting protein 23 or CIPK23) that, turn, appears phosphorylate activate potassium channel, Arabidopsis transporter 1 (AKT1), responsible roots. Here, we report evidence regulatory mechanism more elaborate than earlier envisaged. The recently described part extensive network whereby several CBLs interact with multiple CIPKs activation AKT1. physical interactions among CBL, CIPK, AKT1 components provide specifying members CBL CIPK families functional regulation. interaction between was found involve domain component ankyrin repeat channel. Furthermore, identified 2C-type phosphatase physically interacts inactivates These findings calcium-sensitive together phosphatases form phoshporylation/dephosphorylation regulates channel transport plants.