New methods to study the composition and structure of the extracellular matrix in natural and bioengineered tissues
作者： Jürgen Schiller , Daniel Huster
DOI: 10.4161/BIOM.20866
关键词: Glycosaminoglycan 、 Soft tissue 、 Mechanical strength 、 Biophysics 、 Decreased collagen content 、 Materials science 、 Biomedical engineering 、 Biomechanical Phenomena 、 Extracellular matrix 、 Skeletal tissue 、 Tissue engineering
摘要: The extracellular matrix (ECM) comprises a gel of numerous biopolymers that occurs in multitude biological tissues. ECM provides the basic support and mechanical strength skeletal tissue is responsible for shape retention. At same time, viscoelastic properties elasticity soft As expected, there are several important diseases affect degenerate with severe consequences its properties. Bioengineering promising approach to regenerative capacity body. Unfortunately, biomechanical bioengineered often only poorly meet standards their native counterparts. Many tissues characterized by an increased glycosaminoglycan (GAG) but decreased collagen content. This leads enhanced water content strongly alters thus Therefore, compositional analysis estimate quality. We will ...
sci-hub.se 参考文章(148)
Joseph Zaia, PRINCIPLES OF MASS SPECTROMETRY OF GLYCOSAMINOGLYCANS ,(2005)
H. Puchtler, S. N. Meloan, F. S. Waldrop, Are picro-dye reactions for collagens quantitative? Chemical and histochemical considerations. Histochemistry and Cell Biology. ,vol. 88, pp. 243- 256 ,(1988) , 10.1007/BF00570280
Vikas Prabhakar, Ishan Capila, Ram Sasisekharan, The Structural Elucidation of Glycosaminoglycans Methods of Molecular Biology. ,vol. 534, pp. 147- 156 ,(2009) , 10.1007/978-1-59745-022-5_11
Waclaw Kolodziejski, Solid-state NMR studies of bone. Topics in Current Chemistry. ,vol. 246, pp. 235- 270 ,(2005) , 10.1007/B98652
Jürgen Schiller, Lama Naji, Robert Trampel, Wilfred Ngwa, Robert Knauss, Klaus Arnold, Pulsed-Field Gradient–Nuclear Magnetic Resonance (PFG NMR) to Measure the Diffusion of Ions and Polymers in Cartilage: Applications in Joint Diseases Cartilage and Osteoarthritis. ,vol. 101, pp. 287- 302 ,(2004) , 10.1385/1-59259-821-8:287
D.A. Torchia, [6] Solid state NMR studies of molecular motion in collagen fibrils Methods in Enzymology. ,vol. 82, pp. 174- 186 ,(1982) , 10.1016/0076-6879(82)82063-6
Scott Je, Extracellular matrix, supramolecular organisation and shape. Journal of Anatomy. ,vol. 187, pp. 259- 269 ,(1995)
Daniel Huster, Chapter 4 Solid-State NMR Studies of Collagen Structure and Dynamics in Isolated Fibrils and in Biological Tissues Annual reports on NMR spectroscopy. ,vol. 64, pp. 127- 159 ,(2008) , 10.1016/S0066-4103(08)00004-5
Robert J. Linhardt, Fikri Y. Avci, Toshihiko Toida, Yeong Shik Kim, Miroslaw Cygler, CS Lyases: Structure, Activity, and Applications in Analysis and the Treatment of Diseases Advances in pharmacology (San Diego). ,vol. 53, pp. 187- 215 ,(2006) , 10.1016/S1054-3589(05)53009-6
Michael A. Baldwin, Mass Spectrometers for the Analysis of Biomolecules Methods in Enzymology. ,vol. 402, pp. 3- 48 ,(2005) , 10.1016/S0076-6879(05)02001-X