Cell movement analysis in a necrotactic assay.

作者: Gruler H

DOI:

关键词: Atomic physicsPolarCell movementTrack (disk drive)KinematicsDead cellPhysicsOrientation (geometry)Drift velocityFick's laws of diffusion

摘要: The methods of statistical physics have been applied to analysis cell movement. Human leukocytes (granulocytes) were observed using time-lapse photography. paths the migrating cells determined. chemokinetic response at 35 degrees C is described by diffusion constant (D = 233 micron2/min) and track velocity (25 micron/min). A time-dependent chemotactic gradient created killing an erythrocyte intense laser flash. degree polar orientation (P1 0.85), 24 micron/min, drift towards necrotactic source (v parallel 20 as well show a broad distribution. half-width distribution approximately 5 micron/min. Cell movement can be elementary moving states. characteristic time internal clock 0.5 min. We found that information transfer from 1 bit per change in directed cannot stimulated within period 10 s after last decision adapt new direction.

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