EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 in a time- and dose-dependent manner
作者： Cai-Xia Ma , Yang-Liu Song , Liyun Xiao , Li-Xiang Xue , Wen-Juan Li
DOI: 10.1007/S00018-014-1795-9
关键词: Epidermal growth factor 、 Chromatin immunoprecipitation 、 Cell biology 、 Cellular differentiation 、 Molecular biology 、 Cell culture 、 Signal transduction 、 Biology 、 Regulation of gene expression 、 STAT3 、 Cyclin D1
摘要: … by EGF RNAi or GATA-4 RNAi cannot be rescued by the overexpression of GATA-4 or by EGF … in P19CL6 cells over-expressing GATA-4 and the EGF RNAi cells (1), and in the GATA-4 …
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researchgate.net 参考文章(47)
C. L. Mummery, A. Rochat, A. A. Filipczyk, R. Passier, Cardiovascular development: towards biomedical applicability Cellular and Molecular Life Sciences. ,vol. 64, pp. 704- 718 ,(2007) , 10.1007/S00018-007-6523-2
Susanna Fraguas, Sara Barberán, Francesc Cebrià, EGFR signaling regulates cell proliferation, differentiation and morphogenesis during planarian regeneration and homeostasis Developmental Biology. ,vol. 354, pp. 87- 101 ,(2011) , 10.1016/J.YDBIO.2011.03.023
Jun Wang, Pierre Paradis, Anne Aries, Hiba Komati, Chantal Lefebvre, Hao Wang, Mona Nemer, Convergence of Protein Kinase C and JAK-STAT Signaling on Transcription Factor GATA-4 Molecular and Cellular Biology. ,vol. 25, pp. 9829- 9844 ,(2005) , 10.1128/MCB.25.22.9829-9844.2005
Tetsuro Tamaki, Yoshiyasu Uchiyama, Yoshinori Okada, Kayoko Tono, Maki Masuda, Masahiro Nitta, Akio Hoshi, Akira Akatsuka, Clonal differentiation of skeletal muscle-derived CD34(-)/45(-) stem cells into cardiomyocytes in vivo. Stem Cells and Development. ,vol. 19, pp. 503- 512 ,(2010) , 10.1089/SCD.2009.0179
K. Sakuma, M. Aoki, R. Kannagi, Transcription factors c-Myc and CDX2 mediate E-selectin ligand expression in colon cancer cells undergoing EGF/bFGF-induced epithelial–mesenchymal transition Proceedings of the National Academy of Sciences of the United States of America. ,vol. 109, pp. 7776- 7781 ,(2012) , 10.1073/PNAS.1111135109
Calvin T. Hang, Jin Yang, Pei Han, Hsiu-Ling Cheng, Ching Shang, Euan Ashley, Bin Zhou, Ching-Pin Chang, Chromatin regulation by Brg1 underlies heart muscle development and disease Nature. ,vol. 466, pp. 62- 67 ,(2010) , 10.1038/NATURE09130
Alison C. Brewer, Alexander Alexandrovich, Corey H. Mjaatvedt, Ajay M. Shah, Roger K. Patient, John A. Pizzey, GATA Factors Lie Upstream of Nkx 2.5 in the Transcriptional Regulatory Cascade That Effects Cardiogenesis Stem Cells and Development. ,vol. 14, pp. 425- 439 ,(2005) , 10.1089/SCD.2005.14.425
Mona Nemer, Marko E. Horb, The KLF family of transcriptional regulators in cardiomyocyte proliferation and differentiation. Cell Cycle. ,vol. 6, pp. 117- 121 ,(2007) , 10.4161/CC.6.2.3718
A. Klaus, M. Muller, H. Schulz, Y. Saga, J. F. Martin, W. Birchmeier, Wnt/β-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 109, pp. 10921- 10926 ,(2012) , 10.1073/PNAS.1121236109
Antti Kyrönlahti, Maarit Rämö, Maija Tamminen, Leila Unkila-Kallio, Ralf Butzow, Arto Leminen, Mona Nemer, Nafis Rahman, Ilpo Huhtaniemi, Markku Heikinheimo, Mikko Anttonen, GATA-4 regulates Bcl-2 expression in ovarian granulosa cell tumors. Endocrinology. ,vol. 149, pp. 5635- 5642 ,(2008) , 10.1210/EN.2008-0148