Neurometrics: computer-assisted differential diagnosis of brain dysfunctions.

作者: E. John , L. Prichep , J Fridman , P Easton

DOI: 10.1126/SCIENCE.3336779

关键词: NormativeBrain dysfunctionDementiaDifferential diagnosisCognitionMental healthMedicineNeurometricsDepression (differential diagnoses)Audiology

摘要: Normative developmental equations provide reliable descriptors of brain electrical activity in people 6 to 90 years old. Healthy persons display only chance deviations beyond predicted ranges. Patients with neurological impairment, subtle cognitive dysfunctions, or psychiatric disorders (including dementia and primary depression) show a high incidence abnormal values. The magnitude the increases clinical severity. Different are characterized by distinctive profiles values features. Computerized differential classification some these can be achieved accuracy. Such classification, providing objective corroboration may useful adjunct diagnosis, which relies primarily on subjective impressions. These methods independent criteria for diagnostic validity, evaluations treatment efficacy, more individualized therapy.

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