Cellular Uptake and Antitumor Activity of DOX-hyd-PEG-FA Nanoparticles
作者： Wei-liang Ye , Jiang-bo Du , Bang-le Zhang , Ren Na , Yan-feng Song
DOI: 10.1371/JOURNAL.PONE.0097358
关键词: Drug carrier 、 A549 cell 、 Chemistry 、 Cardiotoxicity 、 Cytotoxicity 、 PEG ratio 、 Cell culture 、 Pharmacology 、 Drug delivery 、 Doxorubicin 、 General Biochemistry, Genetics and Molecular Biology 、 General Agricultural and Biological Sciences 、 General Medicine
摘要: … delivery system using DOX-hyd-PEG-FA nanoparticles (NPs) were prepared. DOX-hyd-PEG-FA … Compared with DOX-hyd-PEG NPs, DOX-hyd-PEG-FA NPs increased the intracellular …
paperity.org参考文章(44)
Patrick Midoux, Chantal Pichon, Jean-Jacques Yaouanc, Paul-Alain Jaffrès, Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers British Journal of Pharmacology. ,vol. 157, pp. 166- 178 ,(2009) , 10.1111/J.1476-5381.2009.00288.X
Philip S Low, Asok C Antony, Folate receptor-targeted drugs for cancer and inflammatory diseases Advanced Drug Delivery Reviews. ,vol. 56, pp. 1055- 1058 ,(2004) , 10.1016/J.ADDR.2004.02.003
Hyuk Sang Yoo, Tae Gwan Park, Folate-receptor-targeted delivery of doxorubicin nano-aggregates stabilized by doxorubicin-PEG-folate conjugate. Journal of Controlled Release. ,vol. 100, pp. 247- 256 ,(2004) , 10.1016/J.JCONREL.2004.08.017
Jun Fang, Hideaki Nakamura, Hiroshi Maeda, The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect Advanced Drug Delivery Reviews. ,vol. 63, pp. 136- 151 ,(2011) , 10.1016/J.ADDR.2010.04.009
Hiroshi MAEDA, Vascular permeability in cancer and infection as related to macromolecular drug delivery, with emphasis on the EPR effect for tumor-selective drug targeting. Proceedings of the Japan Academy. Series B, Physical and biological sciences. ,vol. 88, pp. 53- 71 ,(2012) , 10.2183/PJAB.88.53
Vladimir Torchilin, Tumor delivery of macromolecular drugs based on the EPR effect Advanced Drug Delivery Reviews. ,vol. 63, pp. 131- 135 ,(2011) , 10.1016/J.ADDR.2010.03.011
Yechezkel (Chezy) Barenholz, Doxil®--the first FDA-approved nano-drug: lessons learned. Journal of Controlled Release. ,vol. 160, pp. 117- 134 ,(2012) , 10.1016/J.JCONREL.2012.03.020
Lars Andersson, John Davies, Ruth Duncan, Paolo Ferruti, Jayne Ford, Samantha Kneller, Raniero Mendichi, Gianfranco Pasut, Oddone Schiavon, Clive Summerford, Anders Tirk, Francesco M. Veronese, Veronica Vincenzi, Gefei Wu, Poly(ethylene glycol)-poly(ester-carbonate) block copolymers carrying PEG-peptidyl-doxorubicin pendant side chains: Synthesis and evaluation as anticancer conjugates Biomacromolecules. ,vol. 6, pp. 914- 926 ,(2005) , 10.1021/BM049381P
T. Minko, P. Kopečková, V. Pozharov, J. Kopeček, HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in a human ovarian carcinoma cell line. Journal of Controlled Release. ,vol. 54, pp. 223- 233 ,(1998) , 10.1016/S0168-3659(98)00009-1
Xiao-Bing Xiong, Zengshuan Ma, Raymond Lai, Afsaneh Lavasanifar, The therapeutic response to multifunctional polymeric nano-conjugates in the targeted cellular and subcellular delivery of doxorubicin. Biomaterials. ,vol. 31, pp. 757- 768 ,(2010) , 10.1016/J.BIOMATERIALS.2009.09.080