Studies on a diabetic (KK) strain of the mouse.
作者： Mitsuo Nakamura , Kazuyori Yamada
DOI: 10.1007/BF01222198
关键词:
摘要: This review demonstrates the following points:1. By glucose tolerance test and determination of non-fasting blood sugar values, mice KK strain (a Japanese strain) have been shown to be in a diabetic state. 2. greater than normal body weights, moderate obesity. 3. Pancreatic insulin activity adenohypophyseal growth hormone content are those C75BL mice. 4. The pancreas presents many striking changes, such as hypertrophy hyperplasia islets, degranulation B cells, abundance cell ribosomes endoplasmic reticulum, enlargement Golgi areas diminution zinc insular cells. 5. In other organs (eg. adenohypophysis, liver, adrenal parathyroid) mice, changes also observed. above features discussed relation presumed metabolic disorder
springer.com
sci-hub.se 参考文章(25)
A. A. Like, E. E. Jones, J. Steinke, G. F. Cahill, Pancreatic Studies in Mice with Spontaneous Diabetes Mellitus American Journal of Pathology. ,vol. 46, pp. 621- 644 ,(1965)
Gomori G, Observations with differential stains on human islets of langerhans American Journal of Pathology. ,vol. 17, pp. 395- ,(1941)
B Hellman, C Hellerstrom, The Islets of Langerhans in yellow obese mice. Metabolism-clinical and Experimental. ,vol. 12, pp. 527- ,(1963)
Mitsuo NAKAMURA, A diabetic strain of the mouse. Proceedings of the Japan Academy. ,vol. 38, pp. 348- 352 ,(1962) , 10.2183/PJAB1945.38.348
Mitsuo NAKAMURA, Estimation of adenohypophyseal growth hormone content in the diabetic 'kk' mouse strain by acrylamide gel electrophoresis. Proceedings of the Japan Academy. ,vol. 42, pp. 512- 516 ,(1966) , 10.2183/PJAB1945.42.512
Mitsuo NAKAMURA, Kazuyori YAMADA, A further study of the diabetic(KK)strain of the mouse F1 and F2 offspring of the cross between KK and C57BL/6 mice. Proceedings of the Japan Academy. ,vol. 39, pp. 489- 493 ,(1963) , 10.2183/PJAB1945.39.489
Herbert Elftman, A chrome-alum fixative for the pituitary. Biotechnic & Histochemistry. ,vol. 32, pp. 25- 28 ,(1957) , 10.3109/10520295709111392
HELEN A. PADYKULA, EDITH HERMAN, Factors affecting the activity of adenosine triphosphatase and other phosphatases as measured by histochemical techniques. Journal of Histochemistry and Cytochemistry. ,vol. 3, pp. 161- 169 ,(1955) , 10.1177/3.3.161
RUSSELL J. BARRNETT, RICHARD B. MARSHALL, ARNOLD M. SELIGMAN, HISTOCHEMICAL DEMONSTRATION OF INSULIN IN THE ISLETS OF LANGERHANS1 Endocrinology. ,vol. 57, pp. 419- 438 ,(1955) , 10.1210/ENDO-57-4-419
Kazuyori Yamada, THE CHEMICAL CYTOLOGY OF THE MOUSE PARATHYROID GLAND. Cell and Tissue Research. ,vol. 65, pp. 805- 813 ,(1965) , 10.1007/BF00319302