Effect of drug therapy on compensation from vestibular injury.
作者： Sean B. Peppard
DOI: 10.1002/LARY.1986.96.8.878
关键词:
摘要: The influence of selected drugs on compensation from unilateral labyrinthectomy was studied in the cat. investigated included: a. amphetamine, b. diazepam, c. dimenhydrinate, d. scopolamine, and e. trimethobenzamide. most beneficial for improving recovery were a stimulant (amphetamine) general anti-emetic (trimethobenzamide). It is postulated they had this effect by overall activity level with exercise being known positive influence. Conversely other either little or hindered it, presumably suppressing sensory imbalance vestibular system that essential stimulus to ultimate recovery.
sci-hub.se 参考文章(85)
W. Bechterew, Ergebnisse der Durchschneidung des N. acusticus, nebst Erörterung der Bedeutung der semicirculären Canäle für das Körpergleichgewicht Pflüger, Archiv für die Gesammte Physiologie des Menschen und der Thiere. ,vol. 30, pp. 312- 347 ,(1883) , 10.1007/BF01674334
PAGE NORTHINGTON, EFFECTS OF UNILATERAL AND BILATERAL LABYRINTHECTOMY AND INTRACRANIAL SECTION OF EIGHTH NERVE Archives of Neurology & Psychiatry. ,vol. 32, pp. 51- 71 ,(1934) , 10.1001/ARCHNEURPSYC.1934.02250070057004
W. W. Chambers, J. M. Sprague, Differential Effects of Cerebellar Anterior Lobe Cortex and Fastigial Nuclei on Postural Tonus in the Cat Science. ,vol. 114, pp. 324- 325 ,(1951) , 10.1126/SCIENCE.114.2961.324
Lore Schoen, Quantitative Untersuchungen über die zentrale Kompensation nach einseitiger Urticulusausschaltung bei Fischen Journal of Comparative Physiology A-neuroethology Sensory Neural and Behavioral Physiology. ,vol. 32, pp. 121- 150 ,(1950) , 10.1007/BF00340662
Elisabeth Kolb, Untersuchungen über Zentrale Kompensation und Kompensationsbewegungen einseitig entstateter Frösche Journal of Comparative Physiology A-neuroethology Sensory Neural and Behavioral Physiology. ,vol. 37, pp. 136- 160 ,(1955) , 10.1007/BF00298549
Wolfgang Abeln, Holger Bienhold, Hans Flohr, Influence of cholinomimetics and cholinolytics on vestibu/ar compensation Brain Research. ,vol. 222, pp. 458- 462 ,(1981) , 10.1016/0006-8993(81)91055-6
Robert H. Mathog, Sean B. Peppard, Exercise and recovery from vestibular injury American Journal of Otolaryngology. ,vol. 3, pp. 397- 407 ,(1982) , 10.1016/S0196-0709(82)80017-3
M.L. Giretti, Spinal compensation of the cerebral release phenomena. Experimental Neurology. ,vol. 30, pp. 459- 466 ,(1971) , 10.1016/0014-4886(71)90146-4
R. Llinas, K. Walton, D. Hillman, C. Sotelo, Inferior olive: its role in motor learing. Science. ,vol. 190, pp. 1230- 1231 ,(1975) , 10.1126/SCIENCE.128123
G. B. Azzena, O. Mameli, E. Tolu, Vestibular units during decompensation. Cellular and Molecular Life Sciences. ,vol. 33, pp. 234- 236 ,(1977) , 10.1007/BF02124085