Current synthetic pharmacotherapy for treatment-resistant colorectal cancer: when urgent action is required.

Jesus Esquivel, Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal cancer: Survival outcomes and patient selection Journal of gastrointestinal oncology. ,vol. 7, pp. 72- 78 ,(2016) , 10.3978/J.ISSN.2078-6891.2015.114

Justin Guinney, Rodrigo Dienstmann, Xin Wang, Aurélien De Reynies, Andreas Schlicker, Charlotte Soneson, Laetitia Marisa, Paul Roepman, Gift Nyamundanda, Paolo Angelino, Brian M Bot, Jeffrey S Morris, Iris M Simon, Sarah Gerster, Evelyn Fessler, Felipe De Sousa E Melo, Edoardo Missiaglia, Hena Ramay, David Barras, Krisztian Homicsko, Dipen Maru, Ganiraju C Manyam, Bradley Broom, Valerie Boige, Beatriz Perez-Villamil, Ted Laderas, Ramon Salazar, Joe W Gray, Douglas Hanahan, Josep Tabernero, Rene Bernards, Stephen H Friend, Pierre Laurent-Puig, Jan Paul Medema, Anguraj Sadanandam, Lodewyk Wessels, Mauro Delorenzi, Scott Kopetz, Louis Vermeulen, Sabine Tejpar, None, The consensus molecular subtypes of colorectal cancer Nature Medicine. ,vol. 21, pp. 1350- 1356 ,(2015) , 10.1038/NM.3967

Feriyl Bhaijee, Thomas Huebner, Ralph H. Hruban, Laura D. Wood, Nathan Cuka, Drew M. Pardoll, Nickolas Papadopoulos, Kenneth W. Kinzler, Shibin Zhou, Toby C. Cornish, Janis M. Taube, Robert A. Anders, James R. Eshleman, Bert Vogelstein, Luis A. Diaz, Dung T. Le, Jennifer N. Uram, Hao Wang, Bjarne R. Bartlett, Holly Kemberling, Aleksandra D. Eyring, Andrew D. Skora, Brandon S. Luber, Nilofer S. Azad, Dan Laheru, Barbara Biedrzycki, Ross C. Donehower, Atif Zaheer, George A. Fisher, Todd S. Crocenzi, James J. Lee, Steven M. Duffy, Richard M. Goldberg, Albert de la Chapelle, Minori Koshiji, PD-1 Blockade in Tumors with Mismatch-Repair Deficiency The New England Journal of Medicine. ,vol. 372, pp. 2509- 2520 ,(2015) , 10.1056/NEJMOA1500596

Brian M. Wolpin, Robert J. Mayer, Systemic Treatment of Colorectal Cancer Gastroenterology. ,vol. 134, pp. 1296- 1310.e1 ,(2008) , 10.1053/J.GASTRO.2008.02.098

Jane E. Rogers, Aki Ohinata, Arvind Dasari, Cathy Eng, Atypical metastatic presentations in colorectal cancer: a case series. Clinical Colorectal Cancer. ,vol. 13, ,(2014) , 10.1016/J.CLCC.2013.11.005

Christopher H. Lieu, Lindsay A. Renfro, Aimery de Gramont, Jeffrey P. Meyers, Timothy S. Maughan, Matthew T. Seymour, Leonard Saltz, Richard M. Goldberg, Daniel J. Sargent, S. Gail Eckhardt, Cathy Eng, Association of Age With Survival in Patients With Metastatic Colorectal Cancer: Analysis From the ARCAD Clinical Trials Program Journal of Clinical Oncology. ,vol. 32, pp. 2975- 2982 ,(2014) , 10.1200/JCO.2013.54.9329

Kuppen Pj, Aghdaei Ha, Zali Mr, Nazemalhosseini Mojarad E, The CpG island methylator phenotype (CIMP) in colorectal cancer. Gastroenterology and hepatology from bed to bench. ,vol. 6, pp. 120- 128 ,(2013) , 10.22037/GHFBB.V6I3.383

Chiara Cremolini, Fotios Loupakis, Carlotta Antoniotti, Cristiana Lupi, Elisa Sensi, Sara Lonardi, Silvia Mezi, Gianluca Tomasello, Monica Ronzoni, Alberto Zaniboni, Giuseppe Tonini, Chiara Carlomagno, Giacomo Allegrini, Silvana Chiara, Mauro D'Amico, Cristina Granetto, Marina Cazzaniga, Luca Boni, Gabriella Fontanini, Alfredo Falcone, FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-label, phase 3 TRIBE study The Lancet Oncology. ,vol. 16, pp. 1306- 1315 ,(2015) , 10.1016/S1470-2045(15)00122-9

Chloe E. Atreya, Ryan B. Corcoran, Scott Kopetz, Expanded RAS: Refining the Patient Population Journal of Clinical Oncology. ,vol. 33, pp. 682- 685 ,(2015) , 10.1200/JCO.2014.58.9325

Charlotte EL Klaver, Gijsbert D Musters, Willem A Bemelman, Cornelis JA Punt, Victor J Verwaal, Marcel GW Dijkgraaf, Arend GJ Aalbers, Jarmila DW van der Bilt, Djamila Boerma, Andre JA Bremers, Jacobus WA Burger, Christianne J Buskens, Pauline Evers, Robert J van Ginkel, Wilhelmina MU van Grevenstein, Patrick HJ Hemmer, Ignace HJT de Hingh, Laureen A Lammers, Barbara L van Leeuwen, Wilhelmus JHJ Meijerink, Simon W Nienhuijs, Jolien Pon, Sandra A Radema, Bert van Ramshorst, Petur Snaebjornsson, Jurriaan B Tuynman, Elisabeth A Te Velde, Marinus J Wiezer, Johannes HW de Wilt, Pieter J Tanis, None, Adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with colon cancer at high risk of peritoneal carcinomatosis; the COLOPEC randomized multicentre trial BMC Cancer. ,vol. 15, pp. 428- 428 ,(2015) , 10.1186/S12885-015-1430-7