Amiloride augments TRAIL-induced apoptotic death by inhibiting phosphorylation of kinases and phosphatases associated with the P13K-Akt pathway

作者: Ki M Kim , Yong J Lee

DOI: 10.1038/SJ.ONC.1208213

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摘要: … plasma membrane. This suggests that the plasma membrane bound PTEN mediates the amiloride-induced dephosphorylation (inactivation) of Akt by inhibiting recruitment of Akt to the …

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