Association between Hair-Induced Oronasal Inflammation and Ulcerative Dermatitis in C57BL/6 Mice

摘要: Ulcerative dermatitis (UD) is a genetically linked syndrome that affects the neck, torso, and facial regions of C57BL/6 mice strains with background. In this study, 96 skin ulcerations in 3 different body 40 control animals without ulcerated lesions were evaluated histologically for presence hair-induced inflammation oronasal cavity. We found 73.5% (100 136) had periodontitis, glossitis, or rhinitis regardless absence UD. Of those UD, 93.9% inflammation. The mandibular incisors most commonly affected site (64.6%), followed by maxillary molars (20.8%), (16.7%), tongue nasal cavity (10.4%), (7.3%). addition, occurred 25% (10 40) mice. Here we show significant association between UD inflammatory cavities.