Modeling the electrophoresis and transport of peptides: The effective sphere model and complex formation
作者： Stuart A. Allison , Hongxia Pei , Michelle Allen , Jocelyn Brown , Chang-Il Kim
关键词:
摘要: Modeling the electrophoretic mobility of peptides is examined in this study using a "coarse grained" bead model, or B model for short 8 and also simpler "effective sphere" (ES) model. A comparison between ES models carried out peptide covering broad range ionic strength, charge, length. At strengths lower than approximately 0.013 M, agree to within few percent. The much particular value certain applications such as complex formation other species BGE. behavior oligoglycine borate buffer at high pH can be accounted when included modeling.
sci-hub.se 参考文章(35)
George M Janini, Climaco J Metral, Haleem J Issaq, Gary M Muschik, Peptide mobility and peptide mapping in capillary zone electrophoresis. Experimental determination and theoretical simulation. Journal of Chromatography A. ,vol. 848, pp. 417- 433 ,(1999) , 10.1016/S0021-9673(99)00388-X
J. Th. G. Overbeek, Theorie der Elektrophorese Kolloidchemische Beihefte. ,vol. 54, pp. 287- 364 ,(1943) , 10.1007/BF02556774
George M Janini, Climaco J Metral, Haleem J Issaq, Peptide mapping by capillary zone electrophoresis: How close is theoretical simulation to experimental determination Journal of Chromatography A. ,vol. 924, pp. 291- 306 ,(2001) , 10.1016/S0021-9673(01)00919-0
Dongmei Li, Shilin Fu, Charles A. Lucy, Prediction of electrophoretic mobilities. 3. Effect of ionic strength in capillary zone electrophoresis. Analytical Chemistry. ,vol. 71, pp. 687- 699 ,(1999) , 10.1021/AC980843X
Dušan Koval, Václav Kašička, Iva Zusková, Investigation of the effect of ionic strength of Tris-acetate background electrolyte on electrophoretic mobilities of mono-, di-, and trivalent organic anions by capillary electrophoresis. Electrophoresis. ,vol. 26, pp. 3221- 3231 ,(2005) , 10.1002/ELPS.200500260
Yao Xin, Henrietta Mitchell, Heather Cameron, Stuart A. Allison, Modeling the electrophoretic mobility and diffusion of weakly charged peptides. Journal of Physical Chemistry B. ,vol. 110, pp. 1038- 1045 ,(2006) , 10.1021/JP0544235
Francis Perrin, Mouvement Brownien d'un ellipsoide (II). Rotation libre et dépolarisation des fluorescences. Translation et diffusion de molécules ellipsoidales Journal De Physique Et Le Radium. ,vol. 7, pp. 1- 11 ,(1936) , 10.1051/JPHYSRAD:01936007010100
Mehboob A Survay, David M Goodall, Stephen A.C Wren, Raymond C Rowe, Self-consistent framework for standardising mobilities in free solution capillary electrophoresis: applications to oligoglycines and oligoalanines. Journal of Chromatography A. ,vol. 741, pp. 99- 113 ,(1996) , 10.1016/0021-9673(96)00151-3
Hongxia Pei, Markus W. Germann, Stuart A. Allison, Translational diffusion constants of short peptides: measurement by NMR and their use in structural studies of peptides. Journal of Physical Chemistry B. ,vol. 113, pp. 9326- 9329 ,(2009) , 10.1021/JP902143Q
José García de la Torre, María L. Huertas, Beatriz Carrasco, Calculation of hydrodynamic properties of globular proteins from their atomic-level structure. Biophysical Journal. ,vol. 78, pp. 719- 730 ,(2000) , 10.1016/S0006-3495(00)76630-6