作者: Ernesto Menta , Frank Grams , Ambrogio Oliva , Gerd Zimmermann , Hans-Willi Krell
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摘要: The present invention relates to barbituric acid derivatives of general formula (I) wherein the meanings R, n and A are disclosed in claims. These compounds showed a marked activity as inhibitors metzincins can be used antitumor or antimetastatic agents.