Definition and Measurement of Cell Migration Coefficients

作者: Robert T. Tranquillo , Douglas A. Lauffenburger

DOI: 10.1007/978-3-642-51664-1_32

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摘要: We demonstrate the measurement of cell migration coefficients defined in a constitutive flux expression first proposed by Keller and Segel: random motility coefficient, μ, Chemotaxis χ. Discussion begins with more recent derivations leading to refined expressions defining μ Cell density profiles obtained for leukocytes linear under-agarose assay are then examined consistency theoretical predictions based on derived Alt, yielding values χ which can be interpreted terms fundamental movement parameters using theory. Finally, experimental complications inherent current population assays discussed novel is designed circumvent analyzed.

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