Clinical review: Splanchnic ischaemia

摘要: Inadequate splanchnic perfusion is associated with increased morbidity and mortality, particularly if liver dysfunction coexists. Heart failure, intra-abdominal pressure, haemodialysis the presence of obstructive sleep apnoea are among multiple clinical conditions that impaired in critically ill patients. Total blood flow believed to be relatively protected when gut decreases, because hepatic arterial increases portal venous decreases (the buffer response [HABR]). However, there evidence HABR diminished or even abolished during endotoxaemia becomes very low. Unfortunately, no drugs yet available increase total hepato-splanchnic selectively a clinically relevant extent. The present review discusses old new concepts vasoregulation from both experimental viewpoints. Recently published trials this field discussed.