Mediastinal lymph node staging in suspected lung cancer: comparison of positron emission tomography with F-18-fluorodeoxyglucose and mediastinoscopy.

摘要: Abstract Background In patients with bronchogenic carcinoma, mediastinal lymph node staging is essential for determining treatment options. this retrospective analysis we compared the results of positron emission tomography (PET) using F-18 fluorodeoxyglucose those mediastinoscopy in nodal suspected carcinoma. Methods From March 1997 to June 2001, 102 (86 male,16 female, age 62 ± 9 years) underwent both PET and radiologically disease Total body scans were acquired 90 150 minutes after injection 230 MBq fluorodeoxyglucose. Mediastinoscopic evaluation stations was performed according method Mountain Dresler (1R,1L, 2L, 2R, 4L, 4R,7). Patients eligible if surgical within 6 weeks scan. Results Of patients, benign lesions diagnosed 15. 87 malignant proven by histology, carcinoma found 82. 469 analyzed, malignancy documented histology 84. 79 true-positive 304 true-negative samples found. Five false negative, 81 positive. False-positive findings frequently seen inflammatory lung disease. The sensitivity 94.1%, specificity 79% a diagnostic accuracy 81.6%. positive predictive value 49.3%, negative 98.4%. Conclusions scan histologic verification appears necessary exact staging. view can be omitted whose negative.