Exophthalmos Produced by Injections of Acid Extract of Anterior Pituitary Gland of Cattle

摘要: In former investigations1 we observed that by injections of acid and alkali extracts anterior pituitary cattle, it was possible to produce in the guinea pig changes thyroid gland identical with those very pronounced cases Graves' disease man, namely, a marked hypertrophy hyperplasia acinus cells, softening absorption colloid irregular shape acini, associated often an almost complete disappearance lumen acinus. There also loss weight induced these which indicated hyperactivity gland. Silberberg found administration KI certain extent inhibited changes. This corresponds action this substance disease. Siebert noted rise basal metabolism pigs under influence or more recently simultaneous tends counteract effect on metabolism. Closs, Loeb MacKay1 t...