Impact of participation in a surgical site infection surveillance network: results from a large international cohort study

摘要: Summary Background Surveillance of surgical site infections (SSIs) is a core component effective infection control practices, though its impact has not been quantified on large scale. Aim To determine the time-trend SSI rates in surveillance networks. Methods networks provided procedure-specific data numbers SSIs and operations, stratified by hospitals' year participation surveillance, to capture length as an exposure. Pooled random-effects Poisson regression was performed obtain yearly rate ratios (RRs) with 95% confidence intervals (CIs), including network random intercept. Findings Of 36 invited networks, 17 from 15 high-income countries across Asia, Australia Europe participated study. Aggregated procedures (cardiovascular, digestive, gynaecological-obstetrical, neurosurgical, orthopaedic) were collected, resulting concerning 5,831,737 operations 113,166 SSIs. There significant decrease overall over time, 35% reduction at ninth (final) included (RR: 0.65; CI: 0.63–0.67). variations trends, but strong consistent decreases observed for colorectal surgery, herniorrhaphy, caesarean section, hip prosthesis, knee prosthesis. Conclusion In this large, international cohort study, pooled associated stable sustainable after joining network; causal relationship possible, although unproven. heterogeneity trends. These findings support pivotal role reducing call widespread implementation hospital-based countries.