In vivo activation of the fibrinolytic system of the cat

作者: L. Brian Fleming , Eugene E. Cliffton

DOI: 10.1016/S0022-4804(65)80029-4

关键词:

摘要: Summary Streptokinase and trypsin both produce potent levels of euglobulin fibrinolytic proteolytic activity when introduced into the general circulation cat. produces higher more sustained activity, better activity. Fifty per cent glycerol-saline enhances reduces with or streptokinase but resultant toxicity would preclude practical use glycerol. There is evidence to suggest that particularly high produced by may be associated development a plasminogen activator similar found in man. Hypaque appears inhibit does not itself exhibit properties.

参考文章(18)
LeMar F. Remmert, Philip P. Cohen, Partial purification and properties of a proteolytic enzyme of human serum. Journal of Biological Chemistry. ,vol. 181, pp. 431- 448 ,(1949) , 10.1016/S0021-9258(18)56661-8
Norma Alkjaersig, Anthony P. Fletcher, Sol Sherry, The activation of human plasminogen. I. Spontaneous activation in glycerol. Journal of Biological Chemistry. ,vol. 233, pp. 81- 85 ,(1958) , 10.1016/S0021-9258(19)68031-2
WALTER KOCHOLATY, WILLIAM W. ELLIS, H. JENSEN, Activation of plasminogen by trypsin and plasmin. Blood. ,vol. 7, pp. 882- 890 ,(1952) , 10.1182/BLOOD.V7.9.882.882
Armand J. Quick, The physiology and pathology of hemostasis Lea & Febiger. ,(1951)
Alan J. Johnson, William S. Tillett, THE LYSIS IN RABBITS OF INTRAVASCULAR BLOOD CLOTS BY THE STREPTOCOCCAL FIBRINOLYTIC SYSTEM (STREPTOKINASE) Journal of Experimental Medicine. ,vol. 95, pp. 449- 464 ,(1952) , 10.1084/JEM.95.5.449
G. H. Dunstone, L. B. Fleming, I. A. Porter, D. N. Walder, Experimental in vitro studies on the lysis of blood-clot British Journal of Surgery. ,vol. 51, pp. 227- 234 ,(1964) , 10.1002/BJS.1800510318
Eugene E. Cliffton, Robert L. Clarke, The use of fibrinolytic agents in the treatment of arterial occlusion. American Journal of Surgery. ,vol. 103, pp. 173- 179 ,(1962) , 10.1016/0002-9610(62)90482-8
Paul W. Boyles, William H. Meyer, Jack Graff, Catherine C. Ashley, Robert G. Ripic, Comparative effectiveness of intravenous and intra-arterial fibrinolysin therapy. American Journal of Cardiology. ,vol. 6, pp. 439- 446 ,(1960) , 10.1016/0002-9149(60)90337-4
A. H. FREIMAN, N. U. BANG, E. E. CLIFFTON, Studies on the Production of Intravascular Thrombi and Their Treatment with Fibrinolysin Circulation Research. ,vol. 8, pp. 409- 418 ,(1960) , 10.1161/01.RES.8.2.409