Novel epitheliomesenchymal biphasic stomach tumour (gastroblastoma) in a 9-year-old: morphological, usltrastructural and immunohistochemical findings

作者: D. H. Shin , J. H. Lee , H. J. Kang , K. U. Choi , J. Y. Kim

DOI: 10.1136/JCP.2009.074104

关键词:

摘要: Gastroblastoma is a rare gastric epitheliomesenchymal biphasic tumour composed of spindle and epithelial cells, reported by Miettinen et al in series three cases 2009. All those arose stomachs young adults. Neither the nor mesenchymal component displayed sufficient atypia to diagnose carcinosarcoma or other malignancy. On immunohistochemistry, expressed cytokeratin, was positive for vimentin CD10. designated these neoplasms as gastroblastomas based on their similarities with childhood blastomas such pleuropulmonary blastoma nephroblastoma. This report describes probable fourth case this unique type neoplasm. The present antrum 9-year-old boy. While were evident cases, there some differences. more predominant showed mature morphology. Immunohistochemically, immunolabelling c-KIT CD56. only focally Ultrastructually, desmosomes microvilli found supporting truly lesion.

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