Sonography of pregnancies with first-trimester bleeding and a small intrauterine gestational sac without a demonstrable embryo

作者: P. Falco , S. Zagonari , S. Gabrielli , M. Bevini , G. Pilu

DOI: 10.1002/UOG.2

关键词:

摘要: Objective This was a prospective observational cohort study to evaluate the outcome and prognostic criteria of pregnancies with first-trimester bleeding gestational sac ≤16 mm without demonstrable embryo. Methods Criteria for admission into included: (1) bleeding; (2) transvaginal scan performed upon demonstrating single intrauterine mean diameter embryo. The variable miscarriage, defined as pregnancy loss prior 22 weeks. following explanatory variables were considered: maternal age, menstrual size sac, presence or absence yolk subchorionic hematoma, β-human chorionic gonadotropin levels. relationship these failure analyzed by stepwise logistic regression. Results Of 50 patients, 32 (64%) underwent miscarriage. receiver–operating characteristics (ROC) curve demonstrated high level statistical significance (area under ROC 0.9080, P < 0.000001) regression revealed that this only independently correlated subsequent occurrence miscarriage. Discussion It is commonly accepted in pregnant patients bleeding, demonstration ultrasound an embryo may be compatible viable pregnancy. Our results suggest general finding associated poor outcome, miscarriage occurring two-thirds patients. When small risk greatly increased. In present series, less than −1.34 standard deviations over 90% cases. Copyright © 2002 ISUOG. Published John Wiley & Sons, Ltd.

参考文章(10)
S T Nakajima, H H Ho, J Tieu, B L Lasley, J F O'Connor, J W Overstreet, Characterization of human chorionic gonadotropin in normal and abnormal pregnancies Early pregnancy : biology and medicine : the official journal of the Society for the Investigation of Early Pregnancy. ,vol. 3, pp. 213- 224 ,(1997)
W. Hately, J. Case, S. Campbell, Establishing the death of an embryo by ultrasound: report of a public inquiry with recommendations Ultrasound in Obstetrics and Gynecology. ,vol. 5, pp. 353- 357 ,(1995) , 10.1046/J.1469-0705.1995.05050353.X
T. Tongsong, C. Wanapirak, J. Srisomboon, S. Sirichotiyakul, T. Polsrisuthikul, S. Pongsatha, Transvaginal ultrasound in threatened abortions with empty gestational sacs International Journal of Gynecology & Obstetrics. ,vol. 46, pp. 297- 301 ,(1994) , 10.1016/0020-7292(94)90409-X
C S Levi, E A Lyons, D J Lindsay, Early diagnosis of nonviable pregnancy with endovaginal US. Radiology. ,vol. 167, pp. 383- 385 ,(1988) , 10.1148/RADIOLOGY.167.2.3282258
J F Pedersen, M Mantoni, Prevalence and significance of subchorionic hemorrhage in threatened abortion: a sonographic study. American Journal of Roentgenology. ,vol. 154, pp. 535- 537 ,(1990) , 10.2214/AJR.154.3.2106217
P. Falco, V. Milano, G. Pilu, C. David, G. Grisolia, N. Rizzo, L. Bovicelli, Sonography of pregnancies with first-trimester bleeding and a viable embryo: a study of prognostic indicators by logistic regression analysis Ultrasound in Obstetrics and Gynecology. ,vol. 7, pp. 165- 169 ,(1996) , 10.1046/J.1469-0705.1996.07030165.X
G. Grisolia, K. Milano, G. Pilu, C. Banzi, C. David, S. Gabrielli, N. Rizzo, R. Morandi, L. Bovicelli, Biometry of early pregnancy with transvaginal sonography Ultrasound in Obstetrics and Gynecology. ,vol. 3, pp. 403- 411 ,(1993) , 10.1046/J.1469-0705.1993.03060403.X
S E Rowling, B G Coleman, J E Langer, P H Arger, H L Nisenbaum, S C Horii, First-trimester US parameters of failed pregnancy. Radiology. ,vol. 203, pp. 211- 217 ,(1997) , 10.1148/RADIOLOGY.203.1.9122395
V. Kendrick, B. K. Wittmann, R. D. Wilson, B. Mcgillivray, Spontaneous abortion and pregnancy outcome after normal first-trimester ultrasound examination. Obstetrics & Gynecology. ,vol. 67, pp. 352- 355 ,(1986)
H. A. Sande, O. Reiertsen, E. Fønstelien, P. Torjesen, Evaluation of Threatened Abortion by Human Chorionic Gonadotropin Levels and Ultrasonography International Journal of Gynecology & Obstetrics. ,vol. 18, pp. 123- 127 ,(1980) , 10.1002/J.1879-3479.1980.TB00261.X