Self-reported functional status predicts post-operative outcomes in non-cardiac surgery patients with pulmonary hypertension

作者: Aalap C. Shah , Kevin Ma , David Faraoni , Daniel C. S. Oh , G. Alec Rooke

DOI: 10.1371/JOURNAL.PONE.0201914

关键词:

摘要: BACKGROUND Pulmonary hypertension (PHTN) is associated with increased post-procedure morbidity and mortality. Pre-procedure echocardiography (ECHO) a widely used tool for evaluation of these patients, but its accuracy in predicting outcomes unproven. Self-reported exercise tolerance has not been evaluated operative risk stratification PHTN patients. OBJECTIVE We analyzed whether self-reported predicts (hospital length-of-stay [LOS], mortality morbidity) patients (WHO Class I-V) undergoing anesthesia surgery. METHODS AND FINDINGS reviewed 550 non-cardiac, non-obstetric procedures performed on 370 at single institution between 2007 2013. All had cardiac ECHO documented within 1 year prior to the procedure. comorbidities data were collected. Functional status ( 7 days (p 2 hours < .001), absence systemic = .012). PHORS Score ≥2 was an 30-day major complication rate (28.7% vs. 19.2%; p 0.001) ICU admission (8.6% s 2.8%; .007), no statistical difference hospital readmissions (17.6% 14.0%; .29), or (3.5% 1.4%; .75). Similar findings did further improve outcome prediction. CONCLUSIONS Poor functional severe LOS complications moderate pulmonary different etiologies. A assessment model fair accuracy. thorough underlying etiologies should be undertaken every patient.

参考文章(46)
Omar A Minai, Alejandro C Arroliga, Saiprakash B Venkateshiah, Surgical intervention in patients with moderate to severe pulmonary arterial hypertension. Connecticut medicine. ,vol. 70, pp. 239- 243 ,(2006)
Paul Herijgers, Alexander Van De Bruaene, Werner Budts, Ann Belmans, Marion Delcroix, Jens-Uwe Voigt, Pieter De Meester, Pulmonary arterial pressure and right ventricular dilatation independently determine tricuspid valve insufficiency severity in pre-capillary pulmonary hypertension. Journal of Heart Valve Disease. ,vol. 21, pp. 743- 748 ,(2012)
Vallerie V. McLaughlin, Sanjiv J. Shah, Rogerio Souza, Marc Humbert, Management of Pulmonary Arterial Hypertension Journal of the American College of Cardiology. ,vol. 65, pp. 1976- 1997 ,(2015) , 10.1016/J.JACC.2015.03.540
Gary S. Collins, Johannes B. Reitsma, Douglas G. Altman, Karel G.M. Moons, Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD). Annals of Internal Medicine. ,vol. 162, pp. 735- 736 ,(2015) , 10.7326/L15-5093-2
Kishan S Parikh, Sudarshan Rajagopal, Kristine Arges, Tariq Ahmad, Joseph Sivak, Prashant Kaul, Svati H Shah, Victor Tapson, Eric J Velazquez, Pamela S Douglas, Zainab Samad, None, Use of outcome measures in pulmonary hypertension clinical trials. American Heart Journal. ,vol. 170, pp. 419- 429 ,(2015) , 10.1016/J.AHJ.2015.06.010
Margaret Boult, Stuart Howell, Prue Cowled, Tania De Loryn, Robert Fitridge, Self-reported fitness of American Society of Anesthesiologists class 3 patients undergoing endovascular aneurysm repair predicts patient survival. Journal of Vascular Surgery. ,vol. 62, pp. 299- 303 ,(2015) , 10.1016/J.JVS.2015.03.022
M. Jetté, K. Sidney, G. Blümchen, Metabolic equivalents (METS) in exercise testing, exercise prescription, and evaluation of functional capacity Clinical Cardiology. ,vol. 13, pp. 555- 565 ,(1990) , 10.1002/CLC.4960130809
Friedrich C. Blumberg, Michael Arzt, Tobias Lange, Stephan Schroll, Michael Pfeifer, Roland Wensel, Impact of right ventricular reserve on exercise capacity and survival in patients with pulmonary hypertension. European Journal of Heart Failure. ,vol. 15, pp. 771- 775 ,(2013) , 10.1093/EURJHF/HFT044
Roop Kaw, Vinay Pasupuleti, Abhishek Deshpande, Tarek Hamieh, Esteban Walker, Omar A. Minai, Pulmonary hypertension: An important predictor of outcomes in patients undergoing non-cardiac surgery Respiratory Medicine. ,vol. 105, pp. 619- 624 ,(2011) , 10.1016/J.RMED.2010.12.006