Metabolism at a glance

摘要: Introduction to metabolic pathways Biosynthesis of ATP, part I. ATP: the molecule that powers metabolism II: respiratory chain, and inhibitors uncouplers oxidative phosphorylation The oxidation cytosolic NADH+H+: malate/aspartate shuttle, glycerol phosphate shuttle Metabolism glucose give energy one form 38 molecules ATP glycogen Anaerobic yield as 2,3-Bisphosphoglycerate (2,3-BPG) red blood cell fat (triacylglycerol) fatty acids triacylglycerol pentose pathway production NADPH+H+ pyruvate/malate cycle Mammals cannot synthesize from provide ornithine for urea: 'the urea cycle' non-essential amino Catabolism acids, I II in starvation during period immediately after refeeding protein Disorders acid Amino metabolism, folate 'l-carbon pool', I: purine biosynthesis pyramidine Glycogen III: regulation breakdown synthesis, IV: synthesis (Glycogen synthesis) Regulation glycolysis Krebs gluconeogenesis oxidation, mobilization storage adipose tissue carnitine ketone bodies Ketone body utilization B-Oxidation unsaturated Peroxisomal B-oxidation Elongation desaturation ethanol Sorbitol, galactitol, glucuronate xylitol Fructose Biochemistry diabetes