Adverse clinical outcomes associated with short stature at dialysis initiation: a report of the North American Pediatric Renal Transplant Cooperative Study.

摘要: Objective. We examined whether height less than the 1% for age (z score <-2.5) at dialysis initiation predicts adverse clinical outcomes children with kidney failure. Design. National cohort study of initiating dialysis, followed a minimum 1 month to maximum 8 years. Setting. Voluntary consortium pediatric nephrology centers across United States and Canada in North American Pediatric Renal Transplant Cooperative Study. Patients. Two thousand three hundred six patients ≤21 years old initiated on between 1992 2000. Outcome Measures. School attendance, transplant wait listing, hospitalization rates, survival. Results. Although there were no differences listings, school-aged short stature likely be attending school full-time their counterparts more normal height, even if medically capable. Short-stature have significantly hospital days per follow-up those better growth (mean: 1.92 vs 1.58; median: 0.73 0.44 follow-up). Cox proportional hazards regression analyses show that <1% twofold higher risk death after controlling patient age, race, gender, cause end-stage renal disease, list status, modality. Conclusions. Poor during chronic insufficiency leading is marker complicated course Aggressive nutritional support early referral nephrologist optimize may improve long-term disease. Pediatrics 2002;109:909-913; growth, morbidity.