Impact of Hyperbaric Oxygen on the Healing of Teeth Extraction Sockets and Alveolar Ridge Preservation.

摘要: The purpose of this study was to investigate the role hyperbaric oxygen (HBO) in healing teeth extraction sockets and alveolar ridge preservation. This may provide an experimental basis for widespread application HBO oral implantation. A total 32 beagle dogs were included randomly divided equally between group treated with (100% O2, 2.4 atm, 90 min/day, 5 times/week, 6 weeks) a normobaric (NBO) normal air same chamber. lateral incisors maxillary mandible each dog extracted, right upper lower incisor (A2C2) allowed heal naturally, while left (B2D2) received implants commercial bone substitute. At 4 8 weeks after surgery, clinical observation, cone-beam computerized tomography (CBCT), histomorphology expression levels vascular endothelial growth factor (VEGF) morphogenetic protein 2 (BMP-2) analyzed evaluate new formation, mineralization, reconstruction. After weeks, width lip contour socket NBO significantly reduced collapsed comparison group. CBCT showed that difference vertical height crest labial tongue palatal side smaller than There significant formation (P < 0.05) mineral density groups, greater reconstruction based on histology. Furthermore, VEGF BMP-2 higher resorption promoted early sockets. greatly time preservation, thus showing promise clinic.