Radiation therapy for tumors of the pineal region

摘要: Abstract This manuscript presents the results of treatment for 25 patients with tumors in pineal region and related ectopic locations. Twenty two were treated radiation therapy. Twelve died; autopsies performed on 11 which allowed a definition spread failure patterns. A review literature over 100 case studies was added to present series order increase significance comparisons rates by irradiated brain volumes total doses delivered. The overall median survival these 10 years; at 5 years, 63% alive free disease. data suggests more than 50% probability locations extend direct contiguity or seeding along third ventricle into adjacent supratentorial infratentorial structures. apparent tendency some neoplasms extensively within cranium indicates potential value whole irradiation least use fields that are sufficiently large encompass entire ventricular system. In contrast, low (≤5 10%) metastasis spinal cord after adequate primary therapy does not indicate routine elective irradiation.