Efficacy of laidlomycin propionate to reduce ruminal acidosis in cattle

摘要: Three trials were conducted to evaluate the efficacy of laidlomycin propionate (LP) reduce incidence and severity ruminal acidosis in cattle fed high-grain finishing diets. In each trial, LP was at 0, 6, or 12 mg/kg diet DM. two acidosis-challenge trials, ruminally fistulated steers (DM basis) a 50% concentrate then 95% specific intake (2.75% BW) dosed intraruminally with 100% diet. Laidlomycin did not alter pH total acid concentrations, but Trial 1 6 level altered (P < .10) molar proportions acids, increasing VFA decreasing lactate. 3, reduced day-to-day variation individually during 13-d adaptation period from 65 diet, suggesting subacute acidosis. Feed lower .05) first 13 d trial due affected over entire trial. improved feed efficiency (gain/feed) when calculated on live weight basis (linear, P = carcass .20). does prevent acidosis, it may