Interactions between eotaxin and interleukin-5 in the chemotaxis of primed and non-primed human eosinophils.
作者： Gislaine G. Costa , Reginaldo M. Silva , Carla F. Franco-Penteado , Edson Antunes , Heloisa H.A. Ferreira
DOI: 10.1016/J.EJPHAR.2006.09.075
关键词:
摘要: This study was designed to understand the relationship between interleukin-5 and eotaxin in modulating chemotaxis of eosinophils obtained from healthy subjects with allergic rhinitis. Chemotaxis patients rhinitis toward (0.25 ng/ml) 78% higher than that subjects. Incubation (100 did not change interleukin-5-induced subjects, but it reversed enhanced seen patients. 65% significantly increased eotaxin-induced both subject groups, such increases were markedly for cells Our finding inhibits eosinophil primed suggests this chemokine may downregulate accumulation nasal mucosa
elsevier.com
sci-hub.se 参考文章(46)
A. J. Wardlaw, G. M. Walsh, A. B. Kay, A. R. E. Anwar, O. Cromwell, Adhesion to fibronectin primes eosinophils via alpha 4 beta 1 (VLA-4). Immunology. ,vol. 82, pp. 222- 228 ,(1994)
RA Warringa, HJ Mengelers, PH Kuijper, JA Raaijmakers, PL Bruijnzeel, L Koenderman, In vivo priming of platelet-activating factor-induced eosinophil chemotaxis in allergic asthmatic individuals Blood. ,vol. 79, pp. 1836- 1841 ,(1992) , 10.1182/BLOOD.V79.7.1836.1836
Roger T. Palframan, Paul D. Collins, Timothy J. Williams, Sara M. Rankin, Eotaxin Induces a Rapid Release of Eosinophils and Their Progenitors From the Bone Marrow Blood. ,vol. 91, pp. 2240- 2248 ,(1998) , 10.1182/BLOOD.V91.7.2240
Joachim Lundahl, Ali Moshfegh, Reidar Grönneberg, Gunilla Halldén, EOTAXIN INCREASES THE EXPRESSION OF CD11B/CD18 AND ADHESION PROPERTIES IN IL5, BUT NOT FMLP-PRESTIMULATED HUMAN PERIPHERAL BLOOD EOSINOPHILS Inflammation. ,vol. 22, pp. 123- 135 ,(1998) , 10.1023/A:1022379821130
K. Blaser, C. Walker, P. L. B. Bruijnzeel, J.-C. Virchow, T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma. Journal of Immunology. ,vol. 146, pp. 1829- 1835 ,(1991)
Syed Shahabuddin, Paul Ponath, Robert P. Schleimer, Migration of Eosinophils Across Endothelial Cell Monolayers: Interactions Among IL-5, Endothelial-Activating Cytokines, and C-C Chemokines The Journal of Immunology. ,vol. 164, pp. 3847- 3854 ,(2000) , 10.4049/JIMMUNOL.164.7.3847
William W. Busse, Julie B. Sedgwick, Hideaki Yamamoto, Differential Regulation of Eosinophil Adhesion and Transmigration by Pulmonary Microvascular Endothelial Cells Journal of Immunology. ,vol. 161, pp. 971- 977 ,(1998)
R Sehmi, AJ Wardlaw, O Cromwell, K Kurihara, P Waltmann, AB Kay, Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects. Blood. ,vol. 79, pp. 2952- 2959 ,(1992) , 10.1182/BLOOD.V79.11.2952.2952
Z Allakhverdi, O Ghaffar, Q Hamid, P M Renzi, A D Luster, E A Garcia-Zepada, M D Rothenberg, S Abi-Younes, B Lamkhioued, Increased expression of eotaxin in bronchoalveolar lavage and airways of asthmatics contributes to the chemotaxis of eosinophils to the site of inflammation. Journal of Immunology. ,vol. 159, pp. 4593- 4601 ,(1997)
Gert-Jan Braunstahl, Shelley E. Overbeek, Alex KleinJan, Jan-Bas Prins, Henk C. Hoogsteden, Wytske J. Fokkens, Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways. The Journal of Allergy and Clinical Immunology. ,vol. 107, pp. 469- 476 ,(2001) , 10.1067/MAI.2001.113046