Monoclonal antibody that recognizes an outer membrane antigen common to the pathogenic Neisseria species but not to most nonpathogenic Neisseria species.

摘要: A hybridoma derived from a mouse immunized with gonococcal outer membranes produced an antibody, designated H.8, that bound to all strains of Neisseria gonorrhoeae and N. meningitidis tested, lactamica cinerea, but only rarely other nonpathogenic species. Studies the strain used in production antibody showed surface-exposed, protease-sensitive, heat-modifiable membrane antigen we believe is distinct previously described proteins. Images