Online tracing of molecular weight evolution during radical polymerization via high-resolution FlowNMR spectroscopy
作者： Jeroen H. Vrijsen , Isabel A. Thomlinson , Martin E. Levere , Catherine L. Lyall , Matthew G. Davidson
DOI: 10.1039/D0PY00475H
关键词:
摘要: High-resolution FlowNMR was coupled to a continuous flow reactor monitor polymer molecular weight evolution online by diffusion ordered NMR spectroscopy. Polymers were synthesized reversible addition fragmentation chain transfer polymerization in flow. The setup allows target various lengths dynamic manner without requiring additional purification or sample preparation. Obtaining information this is shown be more accurate than classical SEC analysis at comparable measurement times, with relative errors around 5%.
rsc.org
bath.ac.uk
sci-hub.se 参考文章(38)
Jarosław M. Granda, Liva Donina, Vincenza Dragone, De-Liang Long, Leroy Cronin, Controlling an organic synthesis robot with machine learning to search for new reactivity Nature. ,vol. 559, pp. 377- 381 ,(2018) , 10.1038/S41586-018-0307-8
Maarten Rubens, Jeroen H. Vrijsen, Joachim Laun, Tanja Junkers, Precise Polymer Synthesis by Autonomous Self-Optimizing Flow Reactors. Angewandte Chemie. ,vol. 58, pp. 3183- 3187 ,(2019) , 10.1002/ANIE.201810384
Ruth D. Rittinghaus, Pascal M. Schäfer, Pascal Albrecht, Christian Conrads, Alexander Hoffmann, Agnieszka N. Ksiazkiewicz, Olga Bienemann, Andrij Pich, Sonja Herres‐Pawlis, New Kids in Lactide Polymerization: Highly Active and Robust Iron Guanidine Complexes as Superior Catalysts Chemsuschem. ,vol. 12, pp. 2161- 2165 ,(2019) , 10.1002/CSSC.201900481
Eric Wimmer, Daniel Cortés-Borda, Solène Brochard, Elvina Barré, Charlotte Truchet, François-Xavier Felpin, An autonomous self-optimizing flow machine for the synthesis of pyridine–oxazoline (PyOX) ligands Reaction Chemistry and Engineering. ,vol. 4, pp. 1608- 1615 ,(2019) , 10.1039/C9RE00096H
Peter Sagmeister, Jason D. Williams, Christopher A. Hone, C. Oliver Kappe, Laboratory of the future: a modular flow platform with multiple integrated PAT tools for multistep reactions Reaction Chemistry and Engineering. ,vol. 4, pp. 1571- 1578 ,(2019) , 10.1039/C9RE00087A
Carlo Botha, Johannes Höpfner, Britta Mayerhöfer, Manfred Wilhelm, On-line SEC-MR-NMR hyphenation: Optimization of sensitivity and selectivity on a 62 MHz benchtop NMR spectrometer Polymer Chemistry. ,vol. 10, pp. 2230- 2246 ,(2019) , 10.1039/C9PY00140A
Jeroen De Neve, Joris J. Haven, Simon Harrisson, Tanja Junkers, Deconstructing Oligomer Distributions: Discrete Species and Artificial Distributions Angewandte Chemie. ,vol. 58, pp. 13869- 13873 ,(2019) , 10.1002/ANIE.201906842
Stephen T. Knox, Sam Parkinson, Raphael Stone, Nicholas J. Warren, Benchtop flow-NMR for rapid online monitoring of RAFT and free radical polymerisation in batch and continuous reactors Polymer Chemistry. ,vol. 10, pp. 4774- 4778 ,(2019) , 10.1039/C9PY00982E
Maarten Rubens, Joren Van Herck, Tanja Junkers, Automated Polymer Synthesis Platform for Integrated Conversion Targeting Based on Inline Benchtop NMR ACS Macro Letters. ,vol. 8, pp. 1437- 1441 ,(2019) , 10.1021/ACSMACROLETT.9B00767
Terry McAfee, Curtis W. Jarand, Thomas Zekoski, Rick Montgomery, Wayne F. Reed, Coupling of NMR to ACOMP for Terpolymerization Monitoring and Control Macromolecular Reaction Engineering. ,vol. 13, pp. 1900039- ,(2019) , 10.1002/MREN.201900039