The Expanding Therapeutic Utility of Botulinum Neurotoxins

作者: Elena Fonfria , Jacquie Maignel , Stephane Lezmi , Vincent Martin , Andrew Splevins

DOI: 10.3390/TOXINS10050208

关键词:

摘要: … Botulinum neurotoxin (BoNT) is a major therapeutic agent that is licensed in neurological indications, such as dystonia and spasticity. The BoNT … with kainic acid seizures, and reduced …

参考文章(178)
Andrew Blitzer, Richard Glogau, Fredric Brandt, Jacob M Waugh, Michael Kane, Gary D Monheit, Results of a randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of a botulinum toxin type A topical gel for the treatment of moderate-to-severe lateral canthal lines. Journal of Drugs in Dermatology. ,vol. 11, pp. 38- 45 ,(2012)
Roshni Ramachandran, Carmen Lam, Tony L. Yaksh, Botulinum toxin in migraine: Role of transport in trigemino-somatic and trigemino-vascular afferents. Neurobiology of Disease. ,vol. 79, pp. 111- 122 ,(2015) , 10.1016/J.NBD.2015.04.011
Sabine Pellett, William H. Tepp, Regina C.M. Whitemarsh, Marite Bradshaw, Eric A. Johnson, In vivo onset and duration of action varies for botulinum neurotoxin A subtypes 1-5 Toxicon. ,vol. 107, pp. 37- 42 ,(2015) , 10.1016/J.TOXICON.2015.06.021
Theresa J. Smith, Karen K. Hill, Genetic Diversity Within Clostridium botulinum Serotypes, Botulinum Neurotoxin Gene Clusters and Toxin Subtypes Current Topics in Microbiology and Immunology. ,vol. 364, pp. 1- 20 ,(2012) , 10.1007/978-3-642-33570-9_1
Véronique Marchand-Pauvert, Claire Aymard, Louis-Solal Giboin, Federica Dominici, Alessandro Rossi, Riccardo Mazzocchio, Beyond muscular effects: depression of spinal recurrent inhibition after botulinum neurotoxin A. The Journal of Physiology. ,vol. 591, pp. 1017- 1029 ,(2013) , 10.1113/JPHYSIOL.2012.239178
Laura Restani, Elena Novelli, David Bottari, Paola Leone, Ilaria Barone, Lucia Galli-Resta, Enrica Strettoi, Matteo Caleo, Botulinum Neurotoxin A Impairs Neurotransmission Following Retrograde Transynaptic Transport Traffic. ,vol. 13, pp. 1083- 1089 ,(2012) , 10.1111/J.1600-0854.2012.01369.X
Juan Ramirez-Castaneda, Joseph Jankovic, Cynthia Comella, Khashayar Dashtipour, Hubert H. Fernandez, Zoltan Mari, Diffusion, spread, and migration of botulinum toxin Movement Disorders. ,vol. 28, pp. 1775- 1783 ,(2013) , 10.1002/MDS.25582
Norio Akaike, Min-Chul Shin, Masahito Wakita, Yasushi Torii, Tetsuhiro Harakawa, Akihiro Ginnaga, Keiko Kato, Ryuji Kaji, Shunji Kozaki, Transsynaptic inhibition of spinal transmission by A2 botulinum toxin. The Journal of Physiology. ,vol. 591, pp. 1031- 1043 ,(2013) , 10.1113/JPHYSIOL.2012.242131
Shital H. Bariya, Mukesh C. Gohel, Tejal A. Mehta, Om Prakash Sharma, Microneedles: an emerging transdermal drug delivery system. Journal of Pharmacy and Pharmacology. ,vol. 64, pp. 11- 29 ,(2011) , 10.1111/J.2042-7158.2011.01369.X