Effects of Emotionally-Rated Material on Visual Memory in Alzheimer's Disease in Relation to Medial Temporal Atrophy

摘要: Emotional material tends to be better retrieved in memory than neutral material. This emotional enhancement of may related the attentional effects amygdala's response stimuli. Because early neuropathological changes Alzheimer's disease involve amygdala and hippocampus, it has been suggested that this effect is impaired patients. However inconsistent results have reported. The goal our study was evaluate emotion on picture recognition patients affected by disease, explore link between degree amygdalar hippocampal atrophy. Mild (n = 15) control participants 20) performed an Old/New task using pictures negative, neutral, positive valence. Automated segmentation their high-resolution T1 MRI scans order obtain volumes. Correlation analyses were then volumetric data, memory, memory. An found for (with items being recognized negative ones), with no correlation medial temporal volumes, a significant overall scores Conversely, across group patients; however, correlations loss These tend confirm change structures during course disease.