Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition
作者： Benjamin P Kleinstiver , Michelle S Prew , Shengdar Q Tsai , Nhu T Nguyen , Ved V Topkar
DOI: 10.1038/NBT.3404
关键词:
摘要: CRISPR-Cas9 nucleases target specific DNA sequences using a guide RNA but also require recognition of a protospacer adjacent motif (PAM) by the Cas9 protein. Although longer …
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