An efficient transformation of furano-hydroxychalcones to furanoflavones via base mediated intramolecular tandem O-arylation and C-O bond cleavage: a new approach for the synthesis of furanoflavones.
作者： Rajni Sharma , Ram A. Vishwakarma , Sandip B. Bharate
DOI: 10.1039/C5OB01802A
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摘要: A new and efficient potassium carbonate mediated intramolecular tandem O-arylation followed by C–O bond cleavage of furano-hydroxychalcones is described. The treatment pongamol (1a) ovalitenone (2a) with in DMF led to the direct formation furanoflavones lanceolatin B (3ab) pongaglabrone (4ab) excellent yields. This first report on cyclization via (demethoxylation) produce furanoflavonoids.
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