Overview of the Molecular Steps in Steroidogenesis of the GABAergic Neurosteroids Allopregnanolone and Pregnanolone.

作者: Jennifer J. Liang , Ann M. Rasmusson

DOI: 10.1177/2470547018818555

关键词:

摘要: Allopregnanolone and pregnanolone—neurosteroids synthesized from progesterone in the brain, adrenal gland, ovary testis—have been implicated a range of neuropsychiatric conditions including ...

参考文章(171)
Robert H Purdy, Giovanni Biggio, Stress and neuroactive steroids. International Review of Neurobiology. ,vol. 46, pp. 243- 272 ,(2001) , 10.1016/S0074-7742(01)46065-X
J P Fry, K Y Li, A J Devall, S Cockcroft, J W Honour, T A Lovick, Fluoxetine elevates allopregnanolone in female rat brain but inhibits a steroid microsomal dehydrogenase rather than activating an aldo-keto reductase. British Journal of Pharmacology. ,vol. 171, pp. 5870- 5880 ,(2014) , 10.1111/BPH.12891
Neal G. Simon, Qianxing Mo, Shan Hu, Carrie Garippa, Shi‐fang Lu, Hormonal pathways regulating intermale and interfemale aggression. International Review of Neurobiology. ,vol. 73, pp. 99- 123 ,(2006) , 10.1016/S0074-7742(06)73003-3
Philipp Gut, Markus Zweckstetter, Richard B. Banati, Lost in translocation: The functions of the 18-kD translocator protein. Trends in Endocrinology and Metabolism. ,vol. 26, pp. 349- 356 ,(2015) , 10.1016/J.TEM.2015.04.001
Pedro E Martinez, David R Rubinow, Lynnette K Nieman, Deloris E Koziol, A Leslie Morrow, Crystal E Schiller, Dahima Cintron, Karla D Thompson, Khursheed K Khine, Peter J Schmidt, 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder. Neuropsychopharmacology. ,vol. 41, pp. 1093- 1102 ,(2016) , 10.1038/NPP.2015.246
Jinjiang Fan, Enrico Campioli, Andrew Midzak, Martine Culty, Vassilios Papadopoulos, None, Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation Proceedings of the National Academy of Sciences of the United States of America. ,vol. 112, pp. 7261- 7266 ,(2015) , 10.1073/PNAS.1502670112
P. L. Pedersen, E. B. De Souza, S. H. Snyder, R. R. H. Anholt, The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane. Journal of Biological Chemistry. ,vol. 261, pp. 576- 583 ,(1986) , 10.1016/S0021-9258(17)36131-8