摘要: In recent days, RNA modifications are gaining the interest of biologist worldwide. Till date, a total 171 has been reported, and number may increase with advancing technologies. The mRNA undergoes like m5M, hm5C, m1A, m6A pseudouridine, collectively called as epitranscriptomic alterations, each them their functional significance. modification is most common one which occurs at motif RRm6AACH in mRNA. altered profiles these changes reported multiple cancers. present review discusses dynamic nature enzymes methyltransferase (writer), demethylase (erasers) binding proteins (readers) importance balance between for homeostasis our body functions metabolism, circadian rhythm, immune response, viral replications, embryogenesis cancer development. Nevertheless, main focus on development progression. understanding such differential infancy provide bring about paradigm shift management treatment.
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