The Brazilian comprehensive response to hepatitis C: from strategic thinking to access to interferon-free therapy.

摘要: Hepatitis C affects over 185 million people around the world. This silent disease is responsible for up to 700,000 deaths per year. Despite scientific revolution in diagnosis and treatment, hepatitis control remains a huge challenge due cost of effective medications. In response global outcry epidemic need improve nation’s public health response, Ministry Health Brazil revolutionized treatment by incorporating highly drugs that can be accessed through sustainable universal means. paper describes unique process implementing evidence-informed policy respond update based on estimate prevalence, current international guidelines, cost-effectiveness impact Brazilian Unified System. Through debate an experience report, authors underlie strategic plan implemented according situation analysis emphasized its relatively short-term period. The comprehensive detailed comprising three main objectives: outcomes evaluating new medications at price; elaborate clinical guidelines treat patients; develop awareness campaigns targeted population interest. this scenario, was able obtain unprecedented discount high-medium income country; provided more than 7000 individuals last 2 months 2015; expects 38,000 patients 2016. remarkable applied developed epidemiological data evidence, it motivated engagement country Sustainable Development Goals, which may inspire other developing countries identify ways achieve these goals 2030.