Tissue microarrays and biomarker validation in molecular diagnostics
作者： Martina Storz , Holger Moch
DOI: 10.1007/978-1-4614-4800-6_15
关键词:
摘要: The technology of tissue microarrays (TMAs) was developed against the background decoding human genome and widespread application high-density cDNA microarrays. TMAs facilitate comprehensive molecular profiling cancer specimens with minimal requirements. A TMA is a paraffin block composed multiple specimens. sections provide targets for parallel in situ detection DNA, RNA, protein targets, allowing rapid analysis hundreds markers same set Multiple can be simultaneously investigated different techniques under identical laboratory conditions.
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