A Versatile and Highly Selective Colorimetric Sensor for the Detection of Amines

摘要: The utility of Meldrum's activated furan (MAF) for the colorimetric detection sub ppm levels amines in solution, on solid supports, and as vapors is reported. MAF synthesized one step from inexpensive commercially available starting materials exhibits high selectivity primary secondary presence competing nucleophiles. reaction between furans results a distinct color change, discernable by naked eye. UV/Vis absorption spectroscopy was utilized to monitor reactions solution determine limits. Additionally, solutions were useful stains thin layer chromatography monitoring solid-phase synthesis peptides peptidomimetics. Finally, used detect volatile released fish samples, demonstrating potential food spoilage applications.