Pathways to hysterectomy: insights from longitudinal twin research.

作者: Susan A. Treloar , Nicholas G. Martin , Lorraine Dennerstein , Beverley Raphael , Andrew C. Heath

DOI: 10.1016/S0002-9378(11)91632-9

关键词:

摘要: Objective: We hypothesized that genetic influences act on "liability" to hysterectomy, secular might differentially affect relative importance of and environmental influences, the sources could be identified from reported risk factors. Study Design: Hysterectomy data an Australia-wide volunteer sample female adult monozygotic dizygotic twins are reported. In 1980 through 1982 a mailed questionnaire was completed by 1232 twin pairs 751 (3966 women) Australian Twin Register (wave 1). The same were surveyed 8 years later 2). Results: A total 366 had undergone hysterectomy wave 1 further 198 at 2. twin-pair correlations for liability (0.61 ± 0.06 0.20 0.11 dizygotic) 2 (0.65 0.05 0.32 0.09 monozygotic) indicated substantial contribution. Reported factors accounted only 15% variance. Conclusion: Genetic stable across birth cohorts, but important influence yet identified.

参考文章(26)
C J MacLean, J K Hewitt, M C Neale, L J Eaves, K S Kendler, J M Meyer, Analyzing the relationship between age at onset and risk to relatives. American Journal of Human Genetics. ,vol. 45, pp. 226- 239 ,(1989)
Overview: a current perspective on twin studies of schizophrenia. American Journal of Psychiatry. ,vol. 140, pp. 1413- 1425 ,(1983) , 10.1176/AJP.140.11.1413
Hans Eysenck : consensus and controversy Taylor and Francis. pp. 182- 207 ,(2012) , 10.4324/9780203299449
G Parker, The Parental Bonding Instrument: psychometric properties reviewed. Psychiatric developments. ,vol. 7, pp. 317- 335 ,(1989)
R. Jardine, N.G. Martin, Causes of Variation in Drinking Habits in a Large Twin Sample Acta geneticae medicae et gemellologiae. ,vol. 33, pp. 435- 450 ,(1984) , 10.1017/S0001566000005882
Joanne M. Meyer, Lindon J. Eaves, Estimating genetic parameters of survival distributions: a multifactorial model. Genetic Epidemiology. ,vol. 5, pp. 265- 275 ,(1988) , 10.1002/GEPI.1370050408
S. Ooki, K. Yamada, A. Asaka, K. Hayakawa, Zygosity diagnosis of twins by questionnaire. Acta geneticae medicae et gemellologiae: twin research. ,vol. 39, pp. 109- 115 ,(1990) , 10.1017/S0001566000005626
Joseph C. Gambone, Robert C. Reiter, Joel B. Lench, J. George Moore, The impact of a quality assurance process on the frequency and confirmation rate of hysterectomy American Journal of Obstetrics and Gynecology. ,vol. 163, pp. 545- 550 ,(1990) , 10.1016/0002-9378(90)91195-I
L. J. Eaves, D. W. Fulker, A. C. Heath, The effects of social homogamy and cultural inheritance on the covariances of twins and their parents: a LISREL model. Behavior Genetics. ,vol. 19, pp. 113- 122 ,(1989) , 10.1007/BF01065887