Decision Analytic Modeling: Some Uses in the Evaluation of New Pharmaceuticals

摘要: There has been rapidly growing interest in performing economic evaluations as part of Phase III clinical trials. Even prospective collection data, however, cannot answer all the questions health policy makers, providers, and public have about costs effects new drugs. For example, there may be a need to project data from trials populations, time periods, or settings that were not observed trial.In these cases, decision analytic models allow projection These can take form simple trees they very complex where underlying disease processes well interventions are modeled. They developed using observational studies with intervention studies.These different approaches modeling outlined, examples for coronary heart disease, zidovudine asymptomatic human immunodeficie...