Pattern and Density of Vascularization in Mammalian Testes, Ovaries, and Ovotestes

摘要: According to the classical paradigm, vasculature of embryonic testis is more dense and complex than that ovary, but recent studies based on whole-mount detection Caveolin-1 (CAV1) as an endothelial cell marker, have suggested level ovarian vascularization higher previously assumed. However, this new hypothesis has been neither tested using alternative methodology nor investigated in other mammalian species. In paper, we studied process gonads males females two species, mouse (Mus musculus) Iberian mole (Talpa occidentalis). Our results show pattern very well conserved among mammals, including both pre- postnatal stages development and, at least mole, it irrespectively whether testicular tissue XY or XX. We shown CAV1 present not only cells also prefollicular oocytes population somatic cortical cells. These data clearly establish that: (1) according hypothesis, degree developing ovary lower testis, (2) evolutionarily occurs similarly moles mice, (3) vascular age-dependent increasing significatively puberty. The expression most animal taxa, from nematodes strongly suggests a role for gene female meiosis. © 2012 WILEY PERIODICALS, INC.