Effects of fibric acid derivatives on biliary lipid composition.

摘要: Fenofibrate, a potent analogue of clofibrate, causes changes in biliary lipid composition similar to those seen with clofibrate and other derivatives fibric acid, although there is suggestion that the increase cholesterol content may be accompanied by an phospholipid as well decrease bile acid content. This favor liquid crystal formation, fenofibrate have less propensity cause gallstones than would derivatives. Many factors are also important determining whether supersaturated will result gallstone use this compound should monitored future determine clinical importance these findings.