Monitoring of patients with brainstem hemorrhage: A simultaneous study of quantitative electroencephalography and transcranial Doppler.

摘要: Abstract Objective To explore whether quantitative electroencephalography (QEEG) and transcranial Doppler (TCD) can be used to evaluate patients with acute severe brainstem hemorrhage (ASBH). Methods We prospectively enrolled ASBH assessed their mortality at the 90-day follow-up. The patients' demographic data, serological clinical factors were recorded. Quantitative brain function monitoring was performed using a TCD-QEEG recording system attached patient’s bedside. Results Thirty-one (55.3 ± 10.6 years; 17 men) studied. Mortality 90 days 61.3%. There no significant difference in TCD-related parameters between survival group death (p > 0.05). Among QEEG-related indexes, only (delta + theta)/(alpha beta) ratio (DTABR) (odds 11.555, 95%confidence interval 1.413–94.503, p = 0.022) an independent predictor of outcome; area under ROC curve DTABR 0.921, cut-off point 3.88, sensitivity 79%, specificity 100%. Conclusions In ASBH, QEEG effectively inform prognosis regarding mortality, while TCD cannot. Significance shows promise for informing ASBH.