Characteristics of Infective Endocarditis in a Tertiary Hospital in East China

摘要: The epidemiology, clinical presentation, and treatment of infective endocarditis (IE) has significantly changed over the past few years in developed countries. However, relevant data from developing countries are different remain scarce. objective this study was to evaluate presentations, outcomes IE patients a tertiary hospital East China an 8-year period. This retrospective observational consecutive cases definite or possible as per modified Duke criteria between January 2008 December 2015. A total 135 39 probable were identified. mean age 47.8 ± 15.7 years, with male preponderance (1.9: 1). Degenerative valve disease accounted for 30.5% IE, followed by congenital heart (29.9%) rheumatic (14.9%). Native cardiac valves present 93.7% patients. Echocardiography blood culture performed all patients, whom 55.2% found have large vegetations (≥10 mm) positive rate 60.3%. Streptococcus remained chief causative agent that identified 61.9% culture-positive Glycopeptide antibacterials cephalosporins most frequently used antimicrobial drugs therapy. Seventy-six (43.7%) surgically treated. mortality during stay 10.9%. Our reflected microbiological profile, located China.